Palmitoyl Tripeptide-28 is a biomimetic peptide specifically designed to target the key mechanisms of skin aging. Its primary mode of action is through signal transduction, communicating with dermal cells to promote a more youthful extracellular matrix.
Collagen I Synthesis: Human dermal fibroblast studies showed up to 150% increase in Collagen I production compared to untreated cells.
Fibroblast Activation: Marked increase in metabolic activity and proliferation confirmed its bio-stimulant properties.
Protection: Confirmed ability to inhibit AGEs formation, protecting the existing collagen network.
Wrinkle Reduction: A 12-week study using 5 ppm dosage showed a statistically significant reduction in wrinkle depth and volume, especially in crow's feet.
Firmness & Elasticity: Instrumental measurements (Cutometer) recorded significant improvements after 4 and 8 weeks.
Texture: Data confirmed improved skin smoothness and a visible increase in hydration levels for a radiant complexion.
Safety Profile: Palmitoyl Tripeptide-28 is well-tolerated, non-irritating, and non-sensitizing. It is ideal for sensitive skin formulations.
Synergistic Combinations: Works exceptionally well with Matrixyl 3000, Argireline, Hyaluronic Acid, Niacinamide (B3), and Antioxidants (Vitamin C, E).
Stability: Stable under standard pH conditions (4.0 - 7.0) and resistant to typical cosmetic processing temperatures.
This highly potent ingredient is effective even at very low concentrations. It is suitable for:
Biomimetic peptide with a clear MOA backed by clinical data.
Boosts collagen while fighting glycation simultaneously.
Proven to reduce wrinkles and improve skin firmness.
Cost-effective due to potency at ppm levels.
Gentle on skin and easy to formulate with other actives.
Advanced "signal peptide" story resonates with consumers.
Closed container, dry place, room temperature.
Not animal tested.
No animal-derived components.
No data available.
It acts as a signal peptide that mimics natural tissue repair processes, significantly boosting the synthesis of Collagen types I, III, and IV to improve skin firmness and reduce wrinkles.
The recommended usage level is between 1 to 10 ppm (0.0001% - 0.001%). Its high potency allows it to be effective even at these very low concentrations.
Yes, it has an excellent safety profile and is confirmed to be non-irritating and non-sensitizing, making it suitable for all skin types, including sensitive skin.
Absolutely. It shows excellent compatibility and synergistic effects when used with antioxidants like Vitamin C and E, as well as Niacinamide and Hyaluronic Acid.
Yes, one of its key secondary functions is anti-glycation activity, which helps protect collagen and elastin fibers from becoming stiff and brittle.
Yes, Palmitoyl Tripeptide-28 does not contain any animal-derived components and is not tested on animals.