1. Mechanism of Action (MOA)

Myristoyl Tetrapeptide-12 is a biomimetic lipopeptide engineered to combat visible signs of skin aging by mimicking and enhancing the body's natural tissue-supporting processes.

Extracellular Matrix (ECM) Stimulation:
The peptide's sequence is designed to mimic specific domains of Decorin, a key proteoglycan in the dermal matrix. It functions as a competitive inhibitor of Matrix Metalloproteinases (MMPs), particularly MMP-1, -3, and -9. By binding to these enzymes, it effectively slows the degradation of collagen and elastin, protecting the skin's structural integrity from enzymatic breakdown.

Collagen Fibrillogenesis:
Beyond inhibition, it actively promotes neocollagenesis by stimulating fibroblasts to synthesize new Collagen Type I and III. It also enhances the proper organization and cross-linking of collagen fibrils, leading to a denser, more resilient dermal network.

Restoring Skin Volume:
Through this dual action of "protecting existing" and "building new" structural proteins, it directly addresses the loss of skin volume and the formation of deep wrinkles, such as nasolabial folds.