High-Quality Palmitoyl Dipeptide-7 The Soothing Peptide for Sensitive Skin Manufacturer, Suppliers

Products Name  Palmitoyl Dipeptide-7
CAS No  911813-90-6
INCI Name  Palmitoyl Dipeptide-7
Specification  ≥98% (HPLC)
Molecular Weight  629.9 g/mol (approximately)
Chemical Formula  C₃₃H₆₃N₅O₆
Appearance  White to off-white fine powder
Solubility  Soluble in water, glycerin, and glycols.

Product Description

01

Product Description & MOA

Palmitoyl Dipeptide-7 Mechanism

Mechanism of Action

Palmitoyl Dipeptide-7 is a biomimetic peptide specifically engineered for its potent anti-inflammatory and skin-restoring properties. It modulates the skin's immune response to promote a calm, balanced, and resilient complexion.

Primary Action: Downregulates pro-inflammatory pathways and inhibits critical cytokines like Interleukin-6 (IL-6) and IL-8.

Lipophilicity: The Palmitoyl (C16) chain ensures effective skin penetration to reach target cells in the epidermis.

02

In Vitro Efficacy & Clinical Results

In Vitro Data

  • Reduces secretion of IL-6 by up to 60% or more.
  • Protects keratinocytes and fibroblasts from inflammatory damage.
  • Modulates gene expression involved in inflammatory responses.

Clinical Results

  • Significant reduction in visible redness and stinging.
  • Improved tolerance of potent actives like retinoids and AHAs.
  • Immediate soothing effect reported by participants.
03

Safety & Compatibility

Safety Profile
Ideal Combinations

Safety Profile

Outstanding safety profile: non-irritating, non-sensitizing, and exceptionally well-tolerated. Ideal for all skin types, including sensitive and reactive skin.

Synergistic Combinations

  • With Actives: Acts as a buffer for Retinol, Vit C, and AHAs.
  • With Soothers: Niacinamide, Centella Asiatica, and Beta-Glucan.
  • With Peptides: Works with Palmitoyl Tripeptide-1 (Matrixyl 3000).
04

Recommended Dosage & Formulation

Usage Level

2% to 5%

In the final formulation for optimal results.

Ideal Applications

  • Soothing Serums & Ampoules
  • Sensitive Skin Moisturizers
  • Post-Procedure Care (Laser/Peels)
  • Anti-Redness Day Creams
05

Summary Selling Points

Point 1
Point 2
Point 3

Targeted Anti-Inflammatory

Scientifically proven to calm skin by inhibiting key inflammatory cytokines like IL-6.

Sensitive Skin Solution

Exceptionally safe for calming redness, reactivity, and skin discomfort.

High-Efficacy Enabler

Reduces irritation associated with retinol, allowing for better compliance and results.

Point 4
Point 5
Storage
Storage

Dry place at room temperature

Testing
Animal Testing

Not animal tested

Vegan
Vegan

No animal-derived components

GMO
GMO Status

No data available

Frequently Asked Questions

Q1: What is the main benefit of Palmitoyl Dipeptide-7?

The main benefit is its potent anti-inflammatory action. It specifically targets and reduces the production of Interleukin-6 (IL-6), which helps calm skin redness, swelling, and irritation.

Q2: Is it safe for sensitive skin?

Yes, Palmitoyl Dipeptide-7 has an outstanding safety profile. It is non-irritating and non-sensitizing, making it an ideal choice for reactive and sensitive skin types.

Q3: How does it work with Retinol or Vitamin C?

It acts as a "buffer." When used alongside potent actives like Retinol or Vitamin C, it reduces the associated irritation and redness, allowing users to tolerate high-efficacy products more comfortably.

Q4: What is the recommended usage concentration in cosmetics?

The recommended usage level in final cosmetic formulations is between 2% and 5%.

Q5: Can it be used after clinical skin treatments?

Yes, it is highly recommended for pre- and post-procedure care, such as after laser treatments, chemical peels, or microneedling, to help soothe the skin and accelerate recovery.

Q6: Is this ingredient vegan-friendly?

Yes, Palmitoyl Dipeptide-7 does not contain any animal-derived components and is suitable for vegan formulations.

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