Aogebio Cosmetic
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Palmitoyl Dipeptide-18 is a biomimetic signaling peptide designed to communicate with skin cells to promote a more youthful and healthy appearance. Its mechanism is multi-faceted, primarily focusing on extracellular matrix (ECM) remodeling and anti-irritation.
Extracellular Matrix (ECM) Stimulation & Anti-Wrinkle:
Anti-Inflammatory & Soothing Action:
Enhanced Barrier Function: Through its calming effect and support of the skin's structure, it contributes to a more resilient skin barrier. The Palmitoyl group enhances lipophilicity for improved skin penetration and stability.
• Collagen Synthesis: Upregulates Collagen I, III, and IV in a dose-dependent manner.
• Anti-Inflammatory: Reduces secretion of IL-6 and other inflammatory mediators.
• Fibronectin Production: Significant increase in glycoproteins crucial for tissue repair.
• Instrumental analysis showed reduction in wrinkle depth and volume exceeding 30% in the crow's feet area after 2 months of twice-daily application.
• Visible improvements in overall skin firmness and smoothness.
• Reported reductions in stinging and irritation from other active ingredients like retinoids or AHAs.
Palmitoyl Dipeptide-18 exhibits an excellent safety profile. It is non-irritating, non-sensitizing, and well-tolerated by all skin types, including sensitive skin.
• With Palmitoyl Tripeptide-1: Powerful anti-wrinkle and firming effects.
• With Hyaluronic Acid: Simultaneous hydration and structural support.
• With Antioxidants (Vit C & E): Comprehensive anti-aging protection.
Usage Level: Typically 2% to 5% in the final product.
Combines anti-wrinkle matrix stimulation with proven soothing benefits.
Supported by studies showing visible reduction in wrinkles and firmness.
Enhances efficacy when used in high-performance peptide complexes.
Closed container, dry place, room temperature.
Not animal tested.
No animal-derived components.
No data available.
