Aogebio Cosmetic
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Dipeptide-2 is a bioactive dipeptide that functions through a sophisticated, neuro-physiological pathway targeted at improving skin health and appearance.
Enkephalinase Inhibition: Its primary mechanism is the inhibition of the enzyme enkephalinase, which is responsible for the degradation of endogenous enkephalins.
Enkephalin Potentiation: By inhibiting this enzyme, Dipeptide-2 increases the local concentration and prolongs the activity of neuropeptides with opioid-like activity.
Enkephalinase Inhibition Assay: Confirmed dose-dependent inhibition of enkephalinase activity.
Lymphatic Endothelial Cell Model:
Study Design: Double-blind, 0.05% concentration, 28 days
Non-irritating and well-tolerated for sensitive eye areas. In vitro tests confirm no cytotoxicity at recommended concentrations.
Recommended Concentration: 0.05% - 0.5% in the final product. Highly effective even at low dosages.
Uniquely acts on the enkephalin pathway for natural drainage.
Clinically shown to reduce puffiness by up to 70%.
Bio-mimetic signaling delivers results at very low concentrations.
