Aogebio Cosmetic
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Palmitoyl Tripeptide-8 is a biomimetic signal peptide that operates based on the principle of cell communication. Its mechanism is precise and unique, targeting the neurological aspect of skin sensitivity.
It acts as a "smart switch" to turn off the primary neurological pathway responsible for skin stinging.
Models: Human neuronal cell models, co-cultures of skin cells and sensory neurons.
Key Findings:
Lactic Acid Stinging Test: Statistically significant reduction (over 40%) in self-reported stinging intensity using 4-10 ppm Palmitoyl Tripeptide-8.
Split-Face Clinical Study: Noticeable sensation of rapid comfort within minutes. Visible reduction in redness and roughness after 4-8 weeks.
Tested under recommended conditions, it is non-irritating, non-sensitizing, and exhibits high cytocompatibility. Suitable for all skin types.
Synergistic Combinations: Works with Centella Asiatica, Bisabolol, and Beta-Glucan.
Ideal Partner: Perfect for products with Retinol, Vitamin C, and AHAs/BHAs to reduce associated discomfort.
Recommended Concentration: 1 - 10 ppm (0.0001% - 0.001%). High efficacy at low levels offers excellent cost-in-use.
Applications:
