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Understanding the photochemical dynamics, manufacturing requirements, and market demand for Sulisobenzone.
Benzophenone-4 (also commercially classified as Sulisobenzone, CAS No. 4065-45-6) is a water-soluble UV absorber with a broad extinction coefficient spanning both UVA and UVB spectrum ranges (specifically between 270 nm and 350 nm). Unlike oil-soluble chemical filters, Benzophenone-4 is utilized in aqueous systems to prevent degradation of light-sensitive raw materials, maintain formula coloration, and enhance product shelf-life under exposure to sunlight.
The global demand for Benzophenone-4 is driven by two main sectors: personal care/cosmetics and high-durability polymer/coatings. In cosmetics, it protects colorants, active botanicals, and fragrances from photo-oxidation. The rising global temperature index combined with the tightening of international consumer safety regulations has heightened demand for highly stable, low-impurity batches of water-soluble UV filters from certified production centers.
Formulators often weigh Benzophenone-4 against other water-soluble organic UV filters like Phenylbenzimidazole Sulfonic Acid (Ensulizole). While Ensulizole excels strictly in high-efficiency UVB absorption, Benzophenone-4 provides wider spectral coverage, acting as both an active sunscreen filter and a formulation stabilizer.
| Parameters | Benzophenone-4 (Sulisobenzone) | Ensulizole (PBSA) | Benzophenone-3 (Oxybenzone) |
|---|---|---|---|
| Chemical Formula | C14H12O6S | C13H10N2O3S | C14H12O3 |
| Solubility Profile | Highly Water Soluble (>= 10g/100ml) | Water-soluble (neutralization required) | Oil Soluble |
| UV Coverage | Broadband (270nm - 350nm) | UVB (290nm - 320nm) | Broadband (270nm - 350nm) |
| Formulation Role | Active Filter & Formula Color/Scent Stabilizer | High-SPF Active Sunscreen Agent | Active UV Filter |
| Standard Regulatory Limits | EU: Max 5% | USA: Max 10% | EU: Max 8% | USA: Max 4% | EU: Max 6% | USA: Max 6% |
A premier manufacturer and exporter of cosmetic raw materials and active pharmaceutical ingredients.
Founded in 2013 and headquartered in the prestigious high-tech zone of Xi'an, Xi'an Aoge Biotech Co., Ltd., along with its subsidiaries Xi'an Imaherb Biotech Co., Ltd. and Xi'an Nahanutri Biotech Co., Ltd., has established itself as a leading force in the cosmetics raw materials industry.
Our expansive cooperative factory, spanning 1,000 mu (approximately 165 acres), is equipped with state-of-the-art extraction and synthesis technology. This advanced infrastructure allows us to manufacture a wide array of premium cosmetic raw materials. Our product line includes natural plant extracts specifically designed for organic cosmetics, as well as synthetic ingredients for high-end skincare formulations. These raw materials serve as the foundation for a multitude of skincare, haircare, and makeup products, ensuring superior quality and efficacy throughout the entire production process.
Equipped with advanced instrumentations and backed by a professional R&D team, Aogebio supplies premium-grade Benzophenone-4 UV absorber globally, catering to strict requirements on purity, residual solvents, heavy metals, and stability profiles.
Unlocking cost advantages, advanced engineering pipelines, and supply chain resilience.
Chinese factories leverage a robust upstream industrial base, utilizing direct access to critical intermediates such as benzoyl chloride and resorcinol. This integration guarantees consistent material feeds, neutralizing typical market volatility found elsewhere. Processing units operate at high thermal efficiencies, using advanced continuous-flow microreactors to scale up synthesis with minimal energy waste.
Proximity to key domestic ports (Shanghai, Qingdao, and Tianjin) combined with the extensive railway corridors of Xi'an ensures fast transit routes to international cosmetic manufacturing hubs across North America, Europe, and Southeast Asia. Factories provide door-to-door bulk shipping with climate-controlled containers to prevent humidity and temperature fluctuations during transit.
Historically, low-cost options carried risks of high ash content and trace organic solvents. Modern Chinese manufacturers, particularly Aogebio, have upgraded crystallization and purification methodologies. Through advanced vacuum-drying systems and recrystallization loops, we achieve high-purity crystalline powder that matches or exceeds European standards (USP/EP Grade).
Our in-house analytical laboratories verify compliance to strict international cosmetic standards.
Rigorous quality control is embedded in every step of our production process, from raw material sourcing to final product delivery, guaranteeing that each batch of Benzophenone-4 adheres to the most stringent international standards. Our analytical facilities utilize cutting-edge instruments such as UPLC, HPLC, GC-MS, and ICP-MS to monitor chemical composition, heavy metals, molecular residue levels, and microbiological counts.
How cosmetic chemists incorporate Sulisobenzone across diverse formulations.
One of the primary challenges in clear formulations (especially those packed in transparent PET bottles) is light-induced fading and scent degradation. Adding Benzophenone-4 at a concentration of 0.05% to 0.2% forms an invisible UV shield within the aqueous phase, preserving synthetic and natural colorants (like FD&C Red No. 40 or Blue No. 1) from photobleaching under fluorescent or window sunlight exposure.
For O/W (Oil-in-Water) emulsions, Benzophenone-4 acts as the water-phase UV absorber. When combined synergistically with oil-soluble filters (such as Avobenzone or Ethylhexyl Methoxycinnamate), it generates a broad-spectrum shield that covers both long-wave UVA and short-wave UVB rays, boosting the overall SPF value while reducing the heavy, greasy skin feel associated with purely oil-based UV filters.
Benzophenone-4 contains a sulfonic acid group in its molecular structure, giving it a low pH in water. To prevent skin irritation, formulators neutralize the solution to a pH of 5.5 to 7.0 using agents like Sodium Hydroxide (NaOH) or Triethanolamine (TEA). Once neutralized, it becomes highly compatible with sensitive skin applications without disrupting the skin barrier.
Active biological ingredients, such as vitamins, green tea polyphenols, and unstable peptides, can oxidize when exposed to light. Incorporating Benzophenone-4 helps maintain the bioavailability of these fragile actives, ensuring the product retains its efficacy from the first application to the last drop.
Navigating compliance, supply security, and clean beauty requirements.
Globally, environmental regulators are monitoring organic UV filters. Formulators must ensure their Benzophenone-4 suppliers offer REACH registration (Europe), FDA VCRP compliance (USA), and NMPA registration (China). Maintaining a fully audited trail of analytical reports secures your brand against sudden compliance checks.
At Aogebio, we embrace sustainable practices, striving to minimize our environmental footprint through eco-friendly production methods and responsible sourcing. This includes recycling water loops within our crystalline extraction units and optimizing atom efficiency to reduce industrial waste.
Procuring raw ingredients from single-source distributors poses high supply chain risks. Establishing a direct relationship with a major manufacturer like Aogebio—backed by a 50-ton monthly output and extensive warehousing capabilities—ensures price stability and consistent supply year-round.
Expert technical and regulatory answers regarding Benzophenone-4 UV absorber.
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